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| rubeosis iridis ： ウィキペディア英語版 |
rubeosis iridis
Rubeosis iridis is a medical condition of the iris of the eye in which new abnormal blood vessels (i.e. neovascularization) are found on the surface of the iris.
==Pathophysiology==
It is usually associated with disease processes in the retina, which involve the retina becoming starved of oxygen (ischaemic). The ischemic retina releases a variety of factors, the most important of which is VEGF. These factors stimulate the formation of new blood vessels (angiogenesis). Unfortunately, these new vessels do not have the same characteristics as the blood vessels originally formed in the eye. In addition, new blood vessels can form in areas that do not have them. Specifically, new blood vessels can be observed on the iris. In addition to the blood vessels in the iris, they can grow into the angle of the eye. These blood vessels eventually go through a process called fibrosis which closes the normal physiologic anatomy of the angle. The closing of the angle prevents fluid from leaving the eye resulting in an increase in intraocular pressure. This is called neovascular glaucoma.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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